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Items for "bilirubin"

Do we measure bilirubin correctly anno 2005?

We observed 30% discrepancy between liquid chemistry and dry chemistry analysers for the determination of total bilirubin in human adult serum samples, which were consistent with a 20% overestimation and 10% underestimation relative to a Jendrassik-Grof reference method, respectively...

Keywords: bilirubin, dry chemistry, liquid chemistry, standard reference material (SRM)

05/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Stone or stricture as a cause of extrahepatic cholestasis – do liver function tests predict the diagnosis?

Background: Cholestasis, roughly divided into intrahepatic and extrahepatic forms, is a clinical challenge...

Keywords: bile duct stone, bile duct stricture, bilirubin, cholestasis, jaundice, liver function test

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
An improved laboratory protocol to assess subarachnoid haemorrhage in patients with negative cranial CT scan

Background: The laboratory analysis of cerebrospinal fluid (CSF) plays a key role in considering subarachnoid haemorrhage (SAH) in patients with clinical suspicion, but negative CT scan...

Keywords: bili-excess, bilirubin, blood pigments, cerebrospinal fluid, subarachnoid haemorrhage

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Determination of total bilirubin in whole blood from neonates: results from a French multicenter study

Background: Jaundice is frequent in neonates and can cause severe complications, especially in premature neonates, particularly the risk of developing acute bilirubin encephalopathy...

Keywords: bilirubin, hyperbilirubinemia, jaundice, neonate, point-of-care testing, Spectrophotometry

09/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Analysis of the components of hypertransaminasemia after liver resection

Background: The increase in plasma aspartate (AST) and alanine (ALT) aminotransferase after liver resection is multifactorial, and a major problem is the difficult quantification of the impact of each factor involved.

Methods: Regression analysis of a large series of measurements for 92 hepatectomy patients was carried out to assess in detail the postoperative evolution of AST and ALT, together with related components.

Results: The best correlate of increased AST and ALT on postoperative day 1 was the duration of surgery (T-surg) (r2=0.31 and 0.29), with a lower correlation for intraoperative liver ischemia (T-isch) (r2=0.22 and 0.17, respectively; p<0.001 for all)...

Keywords: alanine aminotransferase, aspartate aminotransferase, bilirubin, liver ischemia, liver resection

03/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Association between peak serum bilirubin and severity of respiratory distress syndrome in infants of less than 30 weeks' gestation

Introduction: Bilirubin can enter the alveolar space where it could inactivate surfactant and act as an anti-oxidant agent.

Objective: To assess the hypothesis that total serum bilirubin level (TSB) may affect the severity of respiratory distress syndrome (RDS) and the need of respiratory supports in preterm infants.

Study design: We performed a retrospective study of 184 preterm infants with RDS, whose peak TSB had a median value of 194.8 ?mol/L (=11.3 mg/dL)...

Keywords: bilirubin, preterm infants, respiratory distress syndrome (RDS)

04/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Die Bilirubinbestimmung – Eine aktuelle Übersicht / Bilirubin measurement – An updated survey

Zusammenfassung Die präzise, richtige und spezifische Bestimmung des Bilirubins und seiner Fraktionen im Serum ist im klinisch-chemischen Laboratorium trotz einer Vielzahl unterschiedlicher Methoden immer noch nicht problemlos möglich...

Keywords: bilirubin, Methoden, Point-of-care Diagnostik, methods, point-of-care diagnostics

01/2008 | LaboratoriumsMedizin, Walter de Gruyter
Bilirubin measurement – an updated survey1

The goal of precise, accurate and specific measurement of bilirubin and its subfractions in serum has not yet been achieved, despite many different methods being available...

Keywords: bilirubin, methods, point-of-care diagnostics

01/2008 | LaboratoriumsMedizin, Walter de Gruyter