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Items for "Bid"

On the mechanism of alkylphosphocholine (APC)-induced apoptosis in tumour cells

Alkylphosphocholines (APCs) represent a new and very encouraging class of antitumour agents that have also been shown to induce apoptosis in tumour cells, but their exact mode of action has still not been elucidated...

Keywords: Bid, caspase activation, mitochondria, mitochondrial membrane permeabilisation, S-NC-2

03/2005 | Biological Chemistry, Walter de Gruyter
Lysosomal cysteine cathepsins: signaling pathways in apoptosis

Apoptosis is the major mechanism by which eukaryotic organisms eliminate potentially dangerous, superfluous and damaged cells...

Keywords: BH3-only protein, Bid, caspases, cathepsins, extrinsic pathway, intrinsic pathway, lysosomes

06/2007 | Biological Chemistry, Walter de Gruyter