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Items for "BCL2L12"

mRNA expression analysis of a variety of apoptosis-related genes, including the novel gene of the BCL2-family, BCL2L12, in HL-60 leukemia cells after treatment with carboplatin and doxorubicin

Apoptosis is a type of programmed cell death involved in many crucial biological processes...

Keywords: BCL2, BCL2L12, carboplatin, caspase, doxorubicin, HL-60

11/2004 | Biological Chemistry, Walter de Gruyter

Expression analysis of BCL2L12, a new member of apoptosis-related genes, in colon cancer

Apoptosis is an active process regulated by a variety of genes. Recently, the molecular cloning, physical mapping and expression analysis of a novel gene of the Bcl-2 family, BCL2L12, was reported...

Keywords: Apoptosis, BCL2L12, colon cancer

09/2004 | Biological Chemistry, Walter de Gruyter

Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells

The BCL2 family of genes (B-cell CLL/lymphoma 2; Bcl-2) plays a pivotal role in the highly regulated process of apoptosis...

Keywords: Apoptosis, BAX, BCL2L12, caspase, FAS, leukemia, methotrexate, topotecan

12/2006 | Biological Chemistry, Walter de Gruyter

Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS

We studied alterations in the mRNA expression levels of BCL2 (Bcl-2), BCL2L12, BAX, FAS and CASPASE-9 genes in the MCF-7 breast cancer cell line in response to treatment with two anticancer drugs...

Keywords: Apoptosis, BAX, breast cancer, BCL2L12, caspase, etoposide, FAS, taxol

08/2006 | Biological Chemistry, Walter de Gruyter

Molecular profile of breast versus ovarian cancer cells in response to treatment with the anticancer drugs cisplatin, carboplatin, doxorubicin, etoposide and taxol

We assessed changes in the apoptosis-related genes BCL2, BAX, BCL2L12, FAS and CASPASE-3 in OVCAR-3 human ovarian cancer cells and BT-20 human breast cancer cells to provide an insight into the molecular mechanisms involved in the response of these cells to treatment with anticancer drugs and to assess their value as potential biomarkers of chemotherapy response in breast and ovarian cancer...

Keywords: BAX, BCL2, BCL2L12, CASPASE-3, FAS, GAPDH

11/2008 | Biological Chemistry, Walter de Gruyter