The main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group...
Keywords: Thrombin inhibitors, azaphenylalanine scaffold, mast cell degranulation, basicity, rat
00/0000 | Thrombosis and Haemostasis, SchattauerGibbs energies of transfer of H+ ion [ΔG0t(w→s)(H+)] from water (w) to different aquo + alcoholic mixtures (s) were calculated using no extrathermodynamic assumptions...
Keywords: Aquo-Alcoholic Mixture, basicity, Dielectric Constant, Free Energy of Transfer of Hydrogen Ion, Gibbs Energy of Hydrogen Ion
08/2007 | Zeitschrift für Physikalische Chemie, Oldenbourg Wissenschaftsverlag