Objective: To compare the efficacy of atosiban with usual management of threatened preterm labor.
Methods: In this prospective, open-label, randomized controlled trial, women admitted to the hospital in threatened preterm labor (between 24 and 34 weeks' gestation) were randomized to receive atosiban or usual care (?-agonists, calcium channel blockers, magnesium sulphate, or any other tocolytic, alone or in combination, and/or bed rest).
Results: In women randomized to receive atosiban (n=295) or usual care (n=290), significantly more women receiving atosiban remained undelivered at 48 h with no alternative tocolytic compared with usual care (77.6% vs...
Keywords: Atosiban, preterm labor, tocolysis, tocolytic therapy
08/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Preterm birth is defined as delivery at <37 completed weeks of pregnancy (World Health Organization)...
Keywords: Atosiban, cervical assessment, corticosteroids, European guidelines, fibronectin, spontaneous preterm labor, tocolytics
10/2006 | Journal of Perinatal Medicine, Walter de Gruyter