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atherogenesis
Items for "atherogenesis"
Hyperhomocysteinemia and arteriosclerosis: historical perspectives
Early concepts of the origin of arteriosclerosis were introduced in the 19th century by Rokitansky and Virchow, who described mural thrombosis, inflammatory damage to arterial intima, increased intimal permeability to plasma, mucoid degeneration of arterial wall, deposition of plasma lipids in plaques, and fibrosis and calcification of plaques...
Keywords: arteriosclerosis, atherogenesis, homocysteine, homocystinuria, Methionine
10/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterMolecular targeting by homocysteine: a mechanism for vascular pathogenesis
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Although there is a growing body of evidence that homocysteine plays a causal role in atherogenesis, specific mechanisms to explain the underlying pathology have remained elusive...
Keywords: Albumin, atherogenesis, disulfide bond, glutathione peroxidase, homocysteine, hyperhomocysteinemia, molecular targeting, pKa, sulfhydryl group, vascular pathogenesis
10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter