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Items for "apolipoprotein A-V"

Apolipoprotein A-V gene polymorphisms in subjects with metabolic syndrome

Background: Genetic variation at the apolipoprotein A-V locus, recently discovered proximal to the APOA1/C3/A4 gene cluster, is associated with elevated triglyceride concentrations, a risk factor for atherosclerosis.

Methods: The goal of our study was to determine the association of two apolipoprotein A-V (APOA5) gene polymorphisms in a group of urban Romanian subjects with the prevalence of the metabolic syndrome...

Keywords: apolipoprotein A-V, gene polymorphism, metabolic syndrome, obesity

04/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Impact of genetic polymorphisms on the risk of lipid disorders in patients on anti-HIV therapy

Active anti-HIV therapy can induce hypertriglyceridemia, low high-density lipoprotein (HDL) and insulin resistance, eventually accompanied by clinical lipodystrophy, associated loss of subcutaneous adipose tissue and an increase in abdominal adiposity...

Keywords: antiretroviral therapy, apolipoprotein A-V, apolipoprotein C-III, apolipoprotein E, dyslipidemia, HIV, lipodystrophy, pharmacogenomics, protease inhibitors, tumor necrosis factor-? (TNF?)

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter