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Angiogenesis
Items for "Angiogenesis"
Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression
Angiopoietin-2 (Ang2) is among the relevant growth factors induced by hypoxia and plays an important role in the initiation of retinal neovascularizations...
Keywords: Angiopoietin-2, pericyte, Angiogenesis, hypoxia, neovascularization
01/2007 | Thrombosis and Haemostasis, SchattauerSynthesis and biological evaluation of a 99mTc-labelled cyclic RGD peptide for imaging the v3 expression
Aim: The v3 integrin is involved in tumour induced angiogenesis and tumour metastasis. We describe the synthesis and evaluation of a 99mTc-labelled RGD analogue for the visualisation of v3 integrin expression...
Keywords: RGD-Peptide, alpha(v)beta3, Integrin, Stabilität, Angiogenese, Tumor Targeting.
01/2004 | Nuklearmedizin, SchattauerEvaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice
Thrombin-activated Factor XIII (FXIIIa), a plasma transglutaminase, stabilizes fibrin clots by crosslinking fibrin chains...
Keywords: Angiogenesis, factor XIII, thrombospondin-1
03/2006 | Thrombosis and Haemostasis, SchattauerHigh urokinase expression contributes to the angiogenic properties of endothelial cells derived from circulating progenitors
Endothelial progenitor cells (EPC) display a unique ability to repair vascular injury and promote neovascularization although the underlying molecular mechanisms remain poorly understood...
Keywords: Endothelial progenitor, urokinase, Angiogenesis, proteolysis
04/2006 | Thrombosis and Haemostasis, SchattauerEarly in vivo anticoagulation inhibits the angiogenic response following hindlimb ischemia in a rodent model
Emerging findings have demonstrated the critical role of blood clotting factors in the formation and stabilization of embryonic blood vessels...
Keywords: Angiogenesis, warfarin, hirudin, heparin, Anticoagulant
07/2006 | Thrombosis and Haemostasis, Schattauer177Lu-labeled-VG76e monoclonal antibody in tumor angiogenesis: A comparative study using DOTA and DTPA chelating systems
Vascular Endothelial Growth Factor (VEGF) is one of the molecules which regulate angiogenesis, a phenomenon observed in many diseases, including cancer...
Keywords: Angiogenesis, VEGF, Monoclonal antibodies, Lutetium-177, DOTA
06/2007 | Radiochimica Acta, Oldenbourg WissenschaftsverlagNF-?B contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor family of cytokines that control vascular and lymphatic endothelium development...
Keywords: Angiogenesis, hypoxia, inflammation, MTF-1, nuclear factor ?B, VEGF
09/2005 | Biological Chemistry, Walter de GruyterAngiotensin I-converting enzyme inhibitor peptides derived from the endostatin-containing NC1 fragment of human collagen XVIII
Extracellular matrix and soluble plasma proteins generate peptides that regulate biological activities such as cell growth, differentiation and migration...
Keywords: ACE inhibitors, Angiogenesis, bradykinin potentiating peptides, endostatin
05/2006 | Biological Chemistry, Walter de GruyterThe tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction
Tissue kallikrein (hK1) cleaves low-molecular-weight kininogen to produce kinin peptide, which binds to kinin receptors and triggers a wide spectrum of biological effects...
Keywords: Angiogenesis, Apoptosis, brain, heart, hypertension, kinin B2 receptor, oxidative stress, tissue kallikrein
06/2006 | Biological Chemistry, Walter de GruyterBone marrow microvascular density and angiogenic growth factors in multiple myeloma
There is evidence that angiogenesis plays an important role in the progression of multiple myeloma (MM)...
Keywords: hepatocyte growth factor, tumor necrosis factor-?, Angiogenesis, Multiple myeloma
10/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter