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Items for "aminothiols"

Elevated plasma cysteinylglycine levels caused by cilastatin-associated antibiotic treatment

Imipenem (thienamycin formamidine), a broad-spectrum ?-lactam antibiotic, is always used in combination with cilastatin in order to avoid the premature breakdown of imipenem by renal tubular dipeptidase...

Keywords: aminothiols, cilastatin, cysteine, cysteinylglycine, glutathione, imipenem

03/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Association of aminothiols with the clinical outcome in hemodialysis patients: comparison of chromatography and immunoassay for homocysteine determination

Background: Controversial results on hyperhomocysteinemia and cardiovascular risk in hemodialysis (HD) could be due in part to the methodology used for homocysteine (Hcy) determination.

Objective: The aim of this study was to compare the influence of the method used for Hcy determination (chromatography or immunoassay) with regard to the association of Hcy with cardiovascular mortality rate in HD patients in a 3-year prospective study.

Methods: A total of 162 patients undergoing HD were included in a cohort study...

Keywords: aminothiols, cardiovascular, chromatography, Hemodialysis, homocysteine, immunoassay

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter