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Items for "Albumin"

Controlled Release of Proteins Bound to Spherical Polyelectrolyte Brushes

We discuss the interaction of proteins dissolved in aqueous solution with spherical polyelectrolyte brushes (SPB)...

Keywords: polyelectrolyte brushes, protein, Adsorption, Albumin, counterions

01/2007 | Zeitschrift für Physikalische Chemie, Oldenbourg Wissenschaftsverlag

Generation of glycogen- and albumin-producing hepatocyte-like cells from embryonic stem cells

We present a novel two-step protocol for the differentiation of embryonic stem (ES) cells into the hepatic lineage...

Keywords: Albumin, ?-fetoprotein, embryonic stem cells, hepatic differentiation, mouse, nestin

10/2004 | Biological Chemistry, Walter de Gruyter

Molecular targeting by homocysteine: a mechanism for vascular pathogenesis

Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Although there is a growing body of evidence that homocysteine plays a causal role in atherogenesis, specific mechanisms to explain the underlying pathology have remained elusive...

Keywords: Albumin, atherogenesis, disulfide bond, glutathione peroxidase, homocysteine, hyperhomocysteinemia, molecular targeting, pKa, sulfhydryl group, vascular pathogenesis

10/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Increased sensitivity in detecting renal impairments by quantitative measurement of marker protein excretion compared to detection of pathological particles in urine sediment analysis

Background: Positive test strip results, pathological particles in urine and the presence of proteinuria are common findings in nephropathies...

Keywords: Albumin, ?1-microglobulin, ?2-macroglobulin, cellular casts, dysmorphic erythrocyte, flow cytometry, IgG, pathological particles in urine, protein pattern, renal biopsy, retinol-binding protein, transferrin, urinalysis, urine sediment

11/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Relationship between serum uric acid, creatinine, albumin and gestational diabetes mellitus

Background: During normal pregnancy, plasma concentrations of creatinine and uric acid normally decrease as a consequence of their increased glomerular filtration...

Keywords: Albumin, creatinine, gestational diabetes, uric acid

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Role of methionine residues of albumin in T-R conversion of hemoglobin

Background: Hemoglobin (Hb) has peroxidase (POD)-like activity. We found that the addition of albumin to human Hb purified from venous erythrocytes increased its POD-like activity.

Methods: We treated human Hb with a Blue-Toyopearl column of immobilized albumin, compared the treated Hb and native Hb for POD-like activity, the level of Hb-bound 2,3-diphosphoglycerate (2,3-DPG), and the absorption spectrum, and found that treatment with albumin released 2,3-DPG from Hb, resulting in a tense-relaxed (T-R) conversion and increased POD-like activity.

Results: The addition of human, mouse, rat, or bovine albumin to human Hb increased its POD-like activity...

Keywords: Albumin, domain, domain I, hemoglobin, Methionine, POD-like activity

09/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Die quantitative Analyse von Markerproteinen im Urin Quantitative analysis of marker proteins in urine

Zusammenfassung

Die Analyse von spezifischen Proteinen im zweiten Morgenurin, bezogen auf den Kreatiningehalt der Probe, erlaubt heute nicht nur den Nachweis oder den Ausschluss von Nierenerkrankungen, sondern darüber hinaus auch die Differenzierung und Verlaufskontrolle von Nephropathien.

Störungen lassen sich aufgrund ihres Markerproteinprofils in solche mit hauptsächlich glomerulärem oder tubulärem Anteil und zusätzlich in weitere Untergruppen einteilen.

Im Zusammenhang mit den Teststreifenresultaten kann die Quelle einer Blutung mit spezifischen Quotienten näher eingegrenzt und Kontaminationen können von tatsächlichen renalen Proteinurien unterschieden werden.

Eine Plausibilitätsprüfung und Interpretation der erhaltenen Ergebnisse ist unbedingt erforderlich...

Keywords: Albumin, ?1-Mikroglobulin, ?2-Mikroglobulin, Expertensystem, Hämaturie, IgG, Leukozyturie, Nephropathie, Proteinurie, Retinol bindendes Protein, transferrin, ?1-microglobulin, ?2-microglobulin, expert system, hematuria, leukocyturia, nephropathy, proteinuria, retinol binding protein

10/2005 | LaboratoriumsMedizin, Walter de Gruyter

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