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Items for "adhesion molecules"

Interaction of N(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs

In diabetes mellitus an increased risk exists for vascular complications. A role for advanced glycation endproducts (AGEs) in the acceleration of vascular disease has been suggested...

Keywords: Carboxymethyllysine, methylglyoxal, HUVECs, endothelial activation, adhesion molecules, human microvascular endothelial cells

00/0000 | Thrombosis and Haemostasis, Schattauer

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin v3 induces signal transduction and enhances plasminogen activation

It has been questioned whether there are receptors for urokinase-type plasminogen activator (uPA) that facilitate plasminogen activation other than the high affinity uPA receptor (uPAR/CD87) since studies of uPAR knockout mice did not support a major role of uPAR in plasminogen activation...

Keywords: Adhesion receptors / integrins, adhesion molecules, cell migration, Angiogenesis and inhibitors, plasminogen activators

03/2006 | Thrombosis and Haemostasis, Schattauer

Cleavage of human 7-domain VCAM-1 (CD106) by thrombin

Vascular cell adhesion molecule 1 (VCAM-1, CD106) is expressed as a type I transmembrane integrin counter-receptor on activated endothelium and mediates white blood cell attachment...

Keywords: adhesion molecules, adhesion receptors/integrins, leukocyte function/activation,leukocyte trafficking/recruitment,thrombin

05/2006 | Thrombosis and Haemostasis, Schattauer

LFA-1 and VLA-4 involved in human high proliferative potential-endothelial progenitor cells homing to ischemic tissue

Cumulative evidences have revealed that endothelial progenitor cell (EPC) transplantation can promote the neovascularization in ischemic tissue, but the mechanism of EPCs homing to the site of ischemia is poorly understood...

Keywords: endothelial progenitor cells, homing, Ischemia, adhesion molecules

12/2006 | Thrombosis and Haemostasis, Schattauer

Autoimmune bullous disorders

Bullous skin diseases represent a group of organ-specific autoimmune disorders characterised by binding of circulating autoantibodies to adhesion molecules of the epidermis and the dermo-epidermal basement membrane zone...

Keywords: adhesion molecules, autoantibodies, basement membrane zone, bullous skin diseases, desmosomes, ELISA, immunofluorescence, sodium chloride-split skin

02/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Increased soluble VCAM-1 serum levels in preeclampsia are not correlated to urinary excretion or circadian blood pressure rhythm

Objective: Soluble vascular cell adhesion molecule-1 (VCAM-1) is known to be elevated in serum of patients with preeclampsia, but there are no data available on the significance of urinary VCAM-1 excretion in preeclampsia...

Keywords: adhesion molecules, blood pressure, circadian rhythm, preeclampsia

03/2005 | Journal of Perinatal Medicine, Walter de Gruyter

Bullöse Autoimmundermatosen Autoimmune bullous disorders

Zusammenfassung

Bullöse Autoimmundermatosen stellen eine Gruppe organspezifischer Autoimmunerkrankungen dar, die pathogenetisch durch die Bindung von zirkulierenden Autoantikörpern an Adhäsionsstrukturen der Epidermis bzw...

Keywords: Adhäsionsstrukturen, Autoantikörper, Basalmembranzone, Bullöse Autoimmundermatosen, Desmosomen, ELISA, Immunfluoreszenz, Kochsalz-Spalthaut, autoantibodies, adhesion molecules, basement membrane zone, bullous skin diseases, desmosomes, immunofluorescence, sodium chloride-split skin

08/2005 | LaboratoriumsMedizin, Walter de Gruyter

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