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Items for "ADAM protease"

C. elegans as a model system to study the function of the COG complex in animal development

The conserved oligomeric Golgi (COG) complex is an octameric protein complex associated with the Golgi apparatus and is required for proper sorting and glycosylation of Golgi resident enzymes and secreted proteins...

Keywords: ADAM protease, Caenorhabditis elegans, COG complex, glycosylation, Golgi enzyme, organogenesis

08/2006 | Biological Chemistry, Walter de Gruyter
Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8

ADAM proteases are type I transmembrane proteins with extracellular metalloprotease domains...

Keywords: ADAM protease, candidate substrates, ectodomain shedding, fluorescence assay, peptide cleavage

03/2006 | Biological Chemistry, Walter de Gruyter