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Items for "aberrant expression"

Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer

Human kallikrein 6 (KLK6) was identified based on its transient upregulation in a primary breast tumor and its subsequent silencing in a metastatic tumor from the same patient...

Keywords: aberrant expression, alternative promoters, breast cancer, DNA methylation, gene silencing, human kallikrein 6 (protease M/zyme/neurosin)

06/2006 | Biological Chemistry, Walter de Gruyter
The epigenetic basis for the aberrant expression of kallikreins in human cancers

The tissue kallikrein gene family consists of 15 genes tandemly arranged on human chromosome 19q13.4...

Keywords: aberrant expression, Cancer, DNA methylation, epigenetic regulation, human tissue kallikreins

06/2006 | Biological Chemistry, Walter de Gruyter