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Items for "177Lu"

Preparation and preliminary biological evaluation of a 177Lu labeled nitroimidazole derivative for possible use in targeted tumor therapy

The preparation and preliminary biological evaluation of a metronidazole-BFCA (bifunctional chelating agent) conjugate labeled with 177Lu is reported...

Keywords: 177Lu, Metronidazole, Tumor hypoxia

06/2006 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag
177Lu-DOTMP: A viable agent for palliative radiotherapy of painful bone metastasis

The suitable nuclear decay characteristics [T1/2=6.73 d, Eβ (max)=497 keV, Eγ=113 keV (6.4%), 208 keV (11%)] as well as the feasibility of large-scale production with adequate specific activity and radionuclidic purity using a moderate flux reactor are important attributes towards 177Lu to be considered as a promising radionuclide for palliative care in painful bone metastasis...

Keywords: 177Lu, DOTMP, Bone pain palliation, Skeletal metastasis

01/2008 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag