The preparation and preliminary biological evaluation of a metronidazole-BFCA (bifunctional chelating agent) conjugate labeled with 177Lu is reported...
Keywords: 177Lu, Metronidazole, Tumor hypoxia
06/2006 | Radiochimica Acta, Oldenbourg WissenschaftsverlagThe suitable nuclear decay characteristics [T1/2=6.73 d, Eβ (max)=497 keV, Eγ=113 keV (6.4%), 208 keV (11%)] as well as the feasibility of large-scale production with adequate specific activity and radionuclidic purity using a moderate flux reactor are important attributes towards 177Lu to be considered as a promising radionuclide for palliative care in painful bone metastasis...
Keywords: 177Lu, DOTMP, Bone pain palliation, Skeletal metastasis
01/2008 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag