SearchPublisher and Institutes
You are here: Home :: Area NEM :: Medical science
Matthias Heinke, Ralf Surber, Helmut Khnert, Gudrun Dannberg, Dirk Prochnau, Hans R. Figulla
Transesophageal left ventricular posterior wall potential in heart failure patients with biventricular pacing / Transsophageales linksventrikulres Potenzial der posterioren Wand bei Patienten mit Herzinsuffizienz und biventrikulrer Stimulation
Keywords: biventricular pacing, cardiac resynchronization, Heart failure, interventricular delay, left ventricular electrocardiography, biventrikulre Stimulation, Herzinsuffizienz, interventrikulres Delay, kardiale Resynchronisation, linksventrikulre Elektrographie
Introduction: Biventricular (BV) pacing is an established therapy for heart failure (HF) patients with intraventricular conduction delay, but not all patients improved clinically. We investigated the interventricular delay (IVD) by means of the transesophageal left ventricular posterior wall potential (LVPWP). Materials and methods, and Results: A total of 18 HF patients (age 629years; 15 males) with NYHA class 3.10.3, LV ejection fraction 227, left bundle branch block and a QRS duration (QRSD) of 17127ms were analyzed using transesophageal LVPWP before implantation of a BV pacing device. The median follow up was 1414months. In 14 responders, IVD was 8125ms with a QRSD/IVD ratio of 2.20.3 with reclassification of NYHA class 3.10.3 to 2.00.5 (p<0.001) and an increase in LV ejection fraction from 227 to 3611 (p0.001) during long-term BV pacing. In four non-responders, transesophageal IVD was significantly smaller at 3011ms (p0.001). Conclusion: Transesophageal IVD may be a useful method to detect responders to BV pacing. Transesophageal LVPWP may be a simple and useful technique to detect clinical responders to BV pacing in HF patients.
Biomedizinische Technik, Walter de Gruyter
Print ISSN: 0013-5585
Volume: 52, 04/2007
Pages: 173 - 179