You are here: Home :: Area NEM :: Medical science :: Human medicine

Gohar Rahimi, Solvejg Rellecke, Peter Mallmann, Frank Nawroth

Course of pregnancy and birth in a patient with Bernard-Soulier syndrome – a case report

Keywords: Bernard-Soulier syndrome, birth, pregnancy

Bernard-Soulier syndrome is a rare autosomal recessive bleeding disorder characterized by platelet dysfunction, the presence of giant platelets, and a prolonged bleeding time. Absent or reduced expression of the platelet glycoprotein (GP) Ib-IX receptor results in the Bernard-Soulier syndrome and is characterized by severe bleeding and macrothrombocytopenia. To our knowledge only ten pregnant patients with this disease have been previously reported. In some patients the pregnancy course was uneventful while in others post-partum hemorrhage and resulting hysterectomy was the most common complication. We present a primiparous female with Bernard-Soulier syndrome who had delayed post-partum hemorrhage and review the literature.

Journal of Perinatal Medicine, Walter de Gruyter

Print ISSN: 1619-3997
Volume: 33, 05/2005
Pages: 264 - 266

Show full article (external site)

Show all available items of this journal

 

Area NEM