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Maja ?ivkovi?, Aleksandra Stankovi?, Dragan Alavanti?

Pentanucleotide TTTTA and G/A –914 DNA Polymorphisms in Apolipoprotein(a) Promoter: Genotyping by Single-Tube PCR

It is known that pentanucleotide repeat polymorphism, consisting of varying number of (TTTTA) repeats in a promoter, is associated with plasma lipoprotein(a) levels. G/A ?914 base substitution has also been correlated with pentanucleotide repeat polymorphism in individuals with high and low lipoprotein(a) levels. To facilitate future analysis of these polymorphisms we have developed a quick and reliable assay for the detection of both polymorphisms in a single polymerase chain reaction.

Clinical Chemical Laboratory Medicine, Walter de Gruyter

Print ISSN: 1434-6621
Volume: 41, 05/2003
Pages: 632 - 633

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