J. A. Brewster, N. J. Shaw, R. G. Farquharson
Neonatal and pediatric outcome of infants born to mothers with Antiphospholipid Syndrome
Objective: To determine any adverse outcome to infants
born to mothers with Antiphospholipid Syndrome (APS).
Design: Case control study with retrospective data collection
and prospective pediatric review.
Setting: Regional Recurrent Miscarriage Clinic based
at a University Teaching Hospital.
Participants: Infants (n = 62) of mothers with APS,
compared to 124 index cases randomly selected from the delivery register, matched for gestation and sex who
delivered between 1992 and 1997.
Results: Sixty two infants born to 55 women with APS
were reviewed to study the neonatal outcome. The prematurity
rate for the group was 10%, compared to 8.5%
for the total hospital population over the same period
of time. Twenty-one percent (21%) had birth weights
less than or equal to the 10th centile, which was not
statistically significant compared to matched controls.
Journal of Perinatal Medicine, Walter de Gruyter
Print ISSN: 1619-3997
Volume: 27, 07/1999
Pages: 183 - 187
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