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Sharlene M. Day, Jennifer L. Reeve, Daniel D. Myers, William P. Fay

Murine thrombosis models

Due to exciting advances in molecular biology, the laboratory mouse has become an important and frequently used model for studying thrombosis. This article reviews several experimental approaches that have been used to study arterial, venous, and microvascular thrombosis in mice. The advantages and limitations of different models are examined. Related topics of mouse anesthesia, phlebotomy, and in vitro hemostasis testing are also reviewed.

Thrombosis and Haemostasis, Schattauer

Print ISSN: 0340-6245
Volume: 92, 09/2004
Pages: 486 - 494

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