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Z. Csiki, I. Garai, J. Varga, G. Szcs, Z. Galajda, C. Andrs, M. Zeher, L. Galuska
Microcirculation of the fingers in Raynauds syndrome: 99mTc-DTPA imaging
Keywords: scintigraphy, microcirculation, DTPA, Raynaud’s syndrome
Aim: We investigated the circulatory characteristics of patients suffering of primary and secondary Raynauds syndrome. Patients, methods: We examined 106 patients presenting with the classical symptoms of Raynauds syndrom (47 primary, 59 secondary) by hand perfusion scintigraphy developed by our Department of Nuclear Medicine. After visual evaluation we analyzed the images semiquantitatively, using the finger to palm ratio. We statistically compared the patients with primary and those with secondary Raynauds syndrome. Results: By visual evaluation we constated regional perfusion disturbances in 42 from 59 patients with secondary Raynauds syndrome. However, this was observed in only 3 from 47 patients with the primary form of this disease. This difference was statistically significant (p<0.001). Semiquantitative analysis showed that the finger/palm ratios (FPR) were significantly lower (p<0.05) for the patients with primary Raynauds syndrome. No differences in the FPR values concerning sex or right and left side. Conclusion: The hand perfusion scintigraphy with 99mTc-DTPA is a noninvasive, cost effective diagnostic tool, which objectively reflects the global and regional microcirculatory abnormalities of the hands, and provides quantitative data for follow-up.
Nuklearmedizin, Schattauer
Print ISSN: 0029-5566
Volume: 44, 01/2005
Pages: 29 - 32