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H. Landgraf

Longterm treatment of POAD with anticoagulants and platelet inhibitors after endovascular procedures and vascular surgery: What is evidence based?

Keywords: Platelet inhibitors, anticoagulants, Peripheral arterial disease, vascular surgery, dilatation

Platelet inhibitors and anticoagulants are used in the longterm treatment after successful infrainguinal bypass grafts as well as endovascular revascularisation procedures. However, evidence of the usefulness of these therapies is limited with respect to efficiency (patency rate, mortality) and safety (bleeding tendency) concerning these indications. Sufficient data are only available for acetylsalicylic acid treatment after implantation of prosthetic bypass grafts, the data basis for the use of antithrombotic medication in venous bypass grafts or following successful balloon angioplasty with or without stent implantation is, however, inconclusive. The recommendation for lifelong therapy with acetylsalicylic acid after infrainguinal bypass surgery and endovascular treatment is based mainly on the concept of prophylactic treatment of manifest atherosclerotic disease.

Hämostaseologie, Schattauer

Print ISSN: 0720-9355
Volume: 26, 01/2006
Pages: 239 - 244

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