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Carlo Dani, Maria F. Reali, Giovanna Bertini, Elena Martelli, Firmino F. Rubaltelli

Liquid ventilation in an infant with persistent interstitial pulmonary emphysema

We present the case of a full term infant affected by diffuse persistent interstitial pulmonary emphysema (PIPE), who was treated with partial liquid ventilation (PLV) after the failure of conventional management. PIPE is a lethal chronic lung disease of unclear pathogenesis. Clinical history, radiological and histological findings confirmed the diagnosis in our patient. PLV applied for 48 hours resulted in a significant improvement in the infant's respiratory function and was not associated with adverse effects.

We concluded that PLV could be effective in prolonging the survival of infants with PIPE; its application represents an effective form of respiratory support in infants with chronic lung disease.

Journal of Perinatal Medicine, Walter de Gruyter

Print ISSN: 1619-3997
Volume: 29, 04/2001
Pages: 158 - 162

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