Yaprak Engin-Üstün, Yusuf Üstün, Aysun Bay Karabulut, Keziban Do?an, M. Mutlu Meydanl?, Bülent Sezgin
Increased adenosine deaminase in hydatidiform mole
Background: The aim of the current study was to investigate levels of adenosine deaminase in plasma of patients with hydatidiform mole.
Methods: Plasma adenosine deaminase levels were determined in 17 women with normal pregnant course, in 17 women with hydatidiform mole, and in 17 non-pregnant healthy volunteers.
Results: Mean adenosine deaminase activity in the hydatidiform mole group was 121.5±24.8 U/L, significantly higher than in the pregnant control (7.8±6.5 U/L; p<0.0001) and non-pregnant control groups (6.4±7.4 U/L; p<0.0001). A cutoff level of 40.5 U/L was found, with both sensitivity and specificity of 100%.
Conclusions: Adenosine deaminase may play a role in the development of hydatidiform mole.
Clin Chem Lab Med 2007;45:78–81.
Clinical Chemical Laboratory Medicine, Walter de Gruyter
Print ISSN: 1434-6621
Volume: 45, 01/2007
Pages: 78 - 81
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