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Durdi Qujeq, Behzad Hidari, Khezroolla Bijani, Hosein Shirdel

Glutathione Peroxidase Activity and Serum Selenium Concentration in Intrinsic Asthmatic Patients

Serum glutathione peroxidase (GSH-Px) activity and selenium concentration were compared in intrinsic asthmatic patients and non-asthmatic control subjects. Serum GSH-Px activity and selenium concentration were assessed in 46 asthmatic patients and 75 age- and sex-matched non-asthmatic subjects by spectrophotometric assay. Mean serum GSH-Px activity was lower in intrinsic asthmatic subjects (9.4±2.6 ?mol NADPH oxidized/min/g of protein) than in non-asthmatic subjects (16.3±2.9 ?mol NADPH oxidized/min/g of protein). Mean serum selenium was lower in intrinsic asthmatic subjects (1.15±0.23 ?M) than in non-asthmatic subjects (1.98±0.27 ?M). Asthmatic patients have significantly lower concentration of selenium and GSH-Px activity measured in serum.

Clinical Chemical Laboratory Medicine, Walter de Gruyter

Print ISSN: 1434-6621
Volume: 41, 02/2003
Pages: 200 - 202

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