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A.-A. Weber

Combination therapy with anticoagulants and platelet-active drugs

Platelets and the coagulation system cannot be regarded as completely separate systems. Both systems become activated upon vessel injury and multiple functional interactions exist. Thus with a combination therapy with anticoagulants and platelet-active drugs, drug interactions relevant for hemostasis must be expected. This includes a synergistic inhibition of the hemostatic system but also possible synergistic effects on bleeding complications. This concise review discusses the clinical efficacy of a combination therapy with anticoagulants and platelet-active drugs in patients with acute coronary syndromes (unstable angina, myocardial infarction).

Hämostaseologie, Schattauer

Print ISSN: 0720-9355
Volume: 22, 01/2002
Pages: 174 - 177

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