You are here: Home :: Area NEM :: Medical science :: Human medicine :: Internal medicine

J. A. Zeller, Ch. C. Eschenfelder, R. Stingele

Coagulation disorders and stroke

Keywords: Ischaemic stroke, coagulation disorders, Thrombophilia

Hereditary and acquired coagulation disorders may play an important role in the pathophysiology of acute ischaemic stroke. Because of the low prevalence of these disorders and the considerable costs of unmindful diagnostic effort, a custom-tailored approach is desirable. Suggestive in favour of a possible prothrombotic clotting disorder are young patients, repeated episodes of thrombosis in the patients history, inappropriate atherosclerotic vascular changes, previous repeated miscarriages in stroke patients, or structural cardiac abnormalities as a patent foramen ovale. Disorders affecting antithrombin III, protein C und S, APC-resistance, the prothrombin mutation, homocysteinaemia, antiphospholipid antibodies, and procoagulatory cellular interaction are discussed.

Hämostaseologie, Schattauer

Print ISSN: 0720-9355
Volume: 26, 01/2006
Pages: 309 - 315

Show full article (external site)

Show all available items of this journal

 

Area NEM