M. Guschmann, W. Henrich, M. Entezami, J. W. Dudenhausen
Chorioangioma – new insights into a well-known problem
I. Results of a clinical and morphological study of 136 cases
Aims. Chorangiomas are rare hamartomatous lesions.
Possible correlations between their occurrence and the
progression of a pregnancy have been objects of discussions
for quite some time.
Methods. In a retrospective study 22439 unselected placentas
were examined for incidences of chorioangiomas,
morphological features and accompanying clinical characteristics.
Results. Chorangiomas occur in 0,61% of pregnancies,
they are mainly microscopically small, and 55% of them
are localized subchorial. The rate of their occurrence rises
almost linearly with maternal age; chorangiomas are
found most often in women who are over 30 years old.
Hypertension and diabetes are found more often in combination
with chorangiomas than they are in otherwise
normal pregnancies. In 72% of all cases girls were born;
in 33% we also observed malfunctions in the maturation
processes of the placental parenchyma, in particular arrested
and delayed maturation of the villi. Premature
births occur approximately three times more often in
chorioangioma pregnancies than in normal ones.
Chorangiomas are often found in primipara and twin
pregnancies.
Journal of Perinatal Medicine, Walter de Gruyter
Print ISSN: 1619-3997
Volume: 31, 03/2003
Pages: 163 - 169
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