Tibor Nyári, Mark Woodward, Gyula Mészáros, János Karsai, László Kovács
Chlamydia trachomatis infection and the risk of perinatal mortality in Hungary
Introduction: Chlamydial infections of the genital tract
are thought to often lead to preterm birth, which is the
most important perinatal problem in Hungary.
Aim of study: A multicenter study was carried out to
determine the prevalence of Chlamydia trachomatis infection,
risk factors for the infection and to relate the
infection to perinatal mortality, accounting for potential
confounding effects.
Methods: The nucleic acid hybridization method
(PACE2 Gen-Probe) was applied for the examination of
Chlamydia trachomatis. Logistic regression analysis
was used to assess risk.
Results: A total of 6156 pregnant women were examined
for the occurrence of Chlamydia trachomatis. The
observed overall rate of chlamydial infection was 5.9%.
Young age (less than 24 years old) (OR and 95% CI:1.6
(1.3–2.0)), unmarried status (1.5 (1.2–1.9)) and the
high unemployment rate (2.1 (1.6–2.7)) were statistically
significant predictors of the infection.
In logistic regression analysis, chlamydial infection (1.9
(1.1–3.3)), high unemployment rate (1.5 (1.2–2.2))
and low birth weight (1.7 (1.1–2.7) were significant
predictors of perinatal mortality.
Conclusions: Testing pregnant women for diseases that
can be transmitted perinatally is an important part of
obstetric care. Screening for C. trachomatis of unmarried
women under 24 years of age is suggested and need
increased observation during labor.
Journal of Perinatal Medicine, Walter de Gruyter
Print ISSN: 1619-3997
Volume: 29, 01/2001
Pages: 55 - 59
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