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D. A. Dorr, W. F. Phillips, S. Phansalkar, S. A. Sims, J. F. Hurdle
Assessing the Difficulty and Time Cost of De-identification in Clinical Narratives
Keywords: Health Insurance Portability and Accountability Act, Computerized Medical Records Systems, medical informatics computing, natural language processing, de-identification
OBJECTIVE: To characterize the difficulty confronting investigators in removing protected health information (PHI) from cross-discipline, free-text clinical notes, an important challenge to clinical informatics research as recalibrated by the introduction of the US Health Insurance Portability and Accountability Act (HIPAA) and similar regulations. METHODS: Randomized selection of clinical narratives from complete admissions written by diverse providers, reviewed using a two-tiered rater system and simple automated regular expression tools. For manual review, two independent reviewers used simple search and replace algorithms and visual scanning to find PHI as defined by HIPAA, followed by an independent second review to detect any missed PHI. Simple automated review was also performed for the easy PHI that are number- or date-based. RESULTS: From 262 notes, 2074 PHI, or 7.9 6.1 per note, were found. The average recall (or sensitivity) was 95.9% while precision was 99.6% for single reviewers. Agreement between individual reviewers was strong (ICC = 0.99), although some asymmetry in errors was seen between reviewers (p = 0.001). The automated technique had better recall (98.5%) but worse precision (88.4%) for its subset of identifiers. Manually de-identifying a note took 87.3 61 seconds on average. CONCLUSIONS: Manual de-identification of free-text notes is tedious and time-consuming, but even simple PHI is difficult to automatically identify with the exactitude required under HIPAA.
Methods of Information in Medicine, Schattauer
Print ISSN: 0026-1270
Volume: 45, 01/2006
Pages: 246 - 252