Wolfgang Henrich, Annette Schmider, Martina Henrich, Joachim W. Dudenhausen
Acute iliac vein thrombosis in pregnancy treated successfully by streptokinase lysis: a case report
Background: Postthrombotic syndrome is an important
late complication after deep vein thrombosis in pregnancy.
Thrombolytic agents are more efficient in preventing
this condition but are rarely used in pregnant
women.
Case: A 22-year-old woman at 29 weeks of gestation
presented with acute iliac vein thrombosis. After application
of a heparin bolus, systemic streptokinase lysis
was performed. Low-dose heparin therapy was continued for the remainder of the, otherwise unremarkable,
pregnancy. Spontaneous delivery of a healthy girl was
without complications and thromboprophylaxis with
low-molecular heparin was continued.
Conclusion: Thrombolysis in pregnancy is possible and
may help to prevent severe long-term sequelae of
thrombosis in young women. Bleeding is a major risk,
which must be considered and therapy should only be
administered under close observation.
Journal of Perinatal Medicine, Walter de Gruyter
Print ISSN: 1619-3997
Volume: 29, 04/2001
Pages: 155 - 157
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