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Christopher P. Price, Jacqui Calvin, Susan A. Walker, Andrew Trull, David J. Newman, Eileen G. Gorman

A Rapid and Sensitive Automated Light Scattering Immunoassay for Serum C-Reactive Protein and the Definition of a Reference Range in Healthy Blood Donors

The increasing interest in the measurement of serum C-reactive protein in relation to the risk stratification of patients with chest pain has demonstrated the need for more sensitive routine methods of measurement, and an accurate definition of the reference range. We report the determination of a reference range in serum samples from 491 blood donors using a particle enhanced turbidimetric immunoassay that has been modified to offer better imprecision within the reference range. The median values were found to be 2.40 and 2.20 mg/l for males and females, respectively, with 95th percentile range of 1.20–5.20 and 0.40–5.40 mg/l respectively.

Clinical Chemical Laboratory Medicine, Walter de Gruyter

Print ISSN: 1434-6621
Volume: 37, 02/1999
Pages: 109 - 113

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