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A. T. Tzallas, P. S. Karvelis, C. D. Katsis, D. I. Fotiadis, S. Giannopoulos, S. Konitsiotis
A Method for Classification of Transient Events in EEG Recordings: Application to Epilepsy Diagnosis
Keywords: EEG, automated epilepsy diagnosis, clustering, Artificial Neural Networks, spike detection, knowledge-based system
OBJECTIVES: The aim of the paper is to analyze transient events in inter-ictal EEG recordings, and classify epileptic activity into focal or generalized epilepsy using an automated method. METHODS: A two-stage approach is proposed. In the first stage the observed transient events of a single channel are classified into four categories: epileptic spike (ES), muscle activity (EMG), eye blinking activity (EOG), and sharp alpha activity (SAA). The process is based on an artificial neural network. Different artificial neural network architectures have been tried and the network having the lowest error has been selected using the hold out approach. In the second stage a knowledge-based system is used to produce diagnosis for focal or generalized epileptic activity. RESULTS: The classification of transient events reported high overall accuracy (84.48%), while the knowledgebased system for epilepsy diagnosis correctly classified nine out of ten cases. CONCLUSIONS: The proposed method is advantageous since it effectively detects and classifies the undesirable activity into appropriate categories and produces a final outcome related to the existence of epilepsy.
Methods of Information in Medicine, Schattauer
Print ISSN: 0026-1270
Volume: 45, 01/2006
Pages: 610 - 621