This article presents an attempt to connect pathogen's properties that play an essential role on the cellular level with the results of a pathogen's activity observed on the population level. Since a disease develops in an individual, the features of the pathogen and the individual determine a disease course and outcome. Clearly, individual responses to a pathogen strongly affect the spread of a disease in a population. This leads to our approach of basing the construction of our epidemic model on a disease model that describes a disease course in an individual because this model takes into account both the properties of a pathogen and an individual.
Print ISSN: 0927-6467
Volume: 19, 08/2004
Pages: 353 - 360