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H. T. Banks, G. M. Kepler, H. K. Nguyen, J. Webster-Cyriaque

Inverse problems and model validation: an example from latent virus reactivation

Keywords: Least squares inverse problems, nonlinear dynamical models, reactivation of latent viruses

We consider a least squares inverse problem with a model for inducer-mediated reactivation of latent viruses. We illustrate the difficulties associated with the lack of sufficient data (quantity as well as form) in such problems. The modeling and estimation efforts described suggest new experiments as well as needed model extensions.

Journal of Inverse and Ill-posed Problems, Walter de Gruyter

Print ISSN: 0928-0219
Volume: 15, 06/2007
Pages: 225 - 241

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