You are here: Home :: Area NEM :: Life sciences :: Biochemistry

T. Dobner, D. Büchner, T. Zeller, H. Wolf, H.H. Niller

Specific Nucleoprotein Complexes within Adenovirus Capsids

Adenoviral DNA was examined within capsids by dimethyl sulfate footprinting. ProteinDNA interactions were visualized through ligationmediated PCR (LMPCR). Signals for protein binding were found adjacent to both inverted terminal repeats (ITR). There were no indications of close protein binding at several other loci of the viral genome. Therefore, adenovirus type 5 seems to contain sequence or locusspecific DNA binding proteins within the virion.

Biological Chemistry, Walter de Gruyter

Print ISSN: 1431-6730
Volume: 382, 10/2001
Pages: 1373 - 1377

Show full article (external site)

Show all available items of this journal

 

Area NEM