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Åke Lundwall, Vimla Band, Michael Blaber, Judith A. Clements, Yves Courty, Eleftherios P. Diamandis, Hans Fritz, Hans Lilja, Johan Malm, Lois J. Maltais, A. Yvonne Olsson, Constantina Petraki, Andreas Scorilas, Georgia Sotiropoulou, Ulf-Håkan Stenman, Car

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

Keywords: Cancer, evolution, hormone, inflammation, kininogen

The human kallikrein locus on chromosome 19q13.3–13.4 contains kallikrein 1 – the tissue kallikrein – and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

Biological Chemistry, Walter de Gruyter

Print ISSN: 1431-6730
Volume: 387, 06/2006
Pages: 637 - 641

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