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Robert Möller, Andrea Csaki, Wolfgang Fritzsche

Molecular Detection with Gold Nanoparticles: Principles and Fields of Application

Affinity-based biochips enable the highly parallel detection of biological molecules with high specificity and sensitivity. The conventional labeling with fluorescence dyes exhibits disadvantages regarding stability and signals influenced by the chemical environment. A novel detection principle based on metal nanoparticles emerged in the last years. It shows an increased signal stability and simple readout. The detection principles will be explained and the resulting advantages regarding a point-of-care application are described.

tm – Technisches Messen, Oldenbourg Wissenschaftsverlag

Print ISSN: 0171-8096
Volume: 70, 12/2003
Pages: 582

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