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Michael J. Schöning, Maryam H. Abouzar, Arshak Poghossian, Yinhua Han, Andreas Offenhäusser, Sven Ingebrandt

Label-free DNA Detection with Silicon Field-Effect Sensors – Real Effects or Artefacts?

Keywords: DNA detection, field-effect sensors, label-free detection method, functional surfaces

The development of diagnostic methods based on DNA microarrays, so-called DNA- or gene chips, offers many promising future applications. At the moment, most DNA chips are based on fluorescence or radioactive marker assays, where the DNA molecules of interest are sensed by probing these markers with different methods. In this article we introduce a direct, label-free, and fully-electronic detection method for DNA, which is based on field-effect sensors.

tm – Technisches Messen, Oldenbourg Wissenschaftsverlag

Print ISSN: 0171-8096
Volume: 74, 09/2007
Pages: 466 - 474

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