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Andreas Kremling, Steffen Klamt, Martin Ginkel, Ernst-Dieter Gilles

Workbench for Model Set Up, Simulation, and Analysis of Cellular Systems

Current research in molecular genetics and success in developing methods for functional genomics and proteomics lead to an unrivaled knowledge on biological systems. Tools that allow for a quantitative description and analysis become therefore more and more important. The paper at hand introduces tools for model set up, dynamical simulation and analysis. The tools were successfully applied for a number of biological model systems. Tool ProMoT supports the automatical generation of model equations; the equations were afterwards solved numerically with Diva. To analyze the structure of and to calculate flux distributions in metabolic networks, the FluxAnalyzer was developed.

it – Information Technology (vormals it+ti), Oldenbourg Wissenschaftsverlag

Print ISSN: 1611-2776
Volume: 46, 01/2004
Pages: 012

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