The reconstruction of pathways builds on genome and biochemical data. It is the ultimate goal to show higher level interactions between the enzymes in a specific genome, especially the different enzyme pathways (in a species or an individual/patient). The flow of metabolites in a pathway network is analysed by different tools such as elementary mode analysis. This leads to the identification of key enzymes and pharmacological targets in the enzyme network.
Print ISSN: 1611-2776
Volume: 46, 01/2004
Pages: 005