You are here: Home :: Area NEM :: Chemistry :: Physical chemistry

H. Seemann, Roland Winter

Volumetric Properties, Compressibilities and Volume Fluctuations in Phospholipid-Cholesterol Bilayers

We conducted detailed measurements of the apparent specific volume of dipalmitoylphosphatidylcholine (DPPC)–cholesterol mixtures in excess water as a function of pressure up to 70MPa (700bar) at 20, 38 and 50°C. The volumetric properties and the isothermal compressibility κ_T of the lipid vesicles were determined at cholesterol concentrations, χ_chol, ranging up to 50mol. The thermodynamic data are compared with other physico-chemical properties of phospholipid–cholesterol mixtures. Furthermore, the thermodynamic properties of the system are discussed in the light of the various T, χ_chol–phase diagrams and computer simulation studies published in the literature.

Zeitschrift für Physikalische Chemie, Oldenbourg Wissenschaftsverlag

Print ISSN: 0942-9352
Volume: 217, 07/2003
Pages: 831

Journal homepage (external site)

Show all available items of this journal

 

Area NEM