You are here: Home :: Area NEM :: Chemistry :: Physical chemistry

A.T.J. Klein, Frank Rösch, Syed M. Qaim

Investigation of ⁵⁰Cr(d,n)⁵¹Mn and ^natCr(p,x)⁵¹Mn processes with respect to the production of the positron emitter ⁵¹Mn

The positron emitter ⁵¹Mn (t_1/2 = 46.2 min, I_β+ = 97%) is of potential interest in positron emission tomography (PET). With a view to optimizing its production route, excitation functions for deuteron induced nuclear reactions on isotopically enriched (~95%) ⁵⁰Cr were determined radiochemically over the energy range of 3 to 13 MeV and for proton induced nuclear reactions on ^natCr in the range of 18 to 38 MeV. Cross sections are presented for the reactions: ⁵⁰Cr(d,2n) ^50mMn, ⁵⁰Cr(d,n) ⁵¹Mn, ⁵⁰Cr(d,t)⁴⁹Cr, ⁵⁰Cr(d,p)⁵¹Cr, ⁵⁰Cr(d,a)⁴⁸V, ⁵²Cr(d,2p)⁵²V, ^natCr(p,x) ⁵¹Mn, ^natCr(p,x)⁵²Mn, ^natCr(p,x)^52mMn, ^natCr(p,x)⁵⁴Mn, ^natCr(p,x)⁴⁸Cr, ^natCr(p,x)⁴⁹Cr, ^natCr(p,x) ⁵¹Cr, ^natCr(p,x)⁴⁸V and ^natCr(p,x)⁴⁵Ti. In the case of proton induced reactions on ^natCr, the isomeric cross section ratio for the isomeric pair ^52m,gMn was also determined. The results are interpreted in terms of the spins of the two isomers concerned. Theoretical thick target yields were derived from the corresponding excitation functions. The maximum achievable thick target yield of ⁵¹Mn is 1.1 GBq/μAh in the case of the ⁵⁰Cr(d,n) ⁵¹Mn reaction at E_d = 14 → 3 MeV, and 3.2 GBq/μAh in the case of the ^natCr(p,x)⁵¹Mn process for E_p = 40 → 20 MeV. The ⁵⁰Cr(d,n) ⁵¹Mn process is the favourable production route for ⁵¹Mn, since the radioisotopic purity is high and a small-sized medical cyclotron is adequate to produce this positron emitter in sufficient quantities.

Radiochimica Acta, Oldenbourg Wissenschaftsverlag

Print ISSN: 0033-8230
Volume: 88, 05/2000
Pages: 253

Journal homepage (external site)

Show all available items of this journal

 

Area NEM