SearchPublisher and Institutes
You are here: Home :: Area NEM :: Chemistry :: Physical chemistry
K. K. Kothari, N. K. Pillarsetty, Kattesh V. Katti, W.A. Volkert
Characterization of complexation reactions of mono- and bidentate-hydroxymethyl phosphine ligands with the organometallic 99mTc(I)(OH2)3(CO)3+ synthon
The complexation reactions of the 99mTc(I)- (CO)3(OH2)3+ precursor with tris-hydroxymethylenephosphine (THP) and a diphosphine ligand analogue (HMPE) were studied at tracer levels. Results demonstrate rapid formation of 99mTc(I)(CO)3+ complexes with both THP and HMPE. In the presence of excess THP, conversion of initial complexes to stable, well-defined 99mTc species occurs indicating coordination of phosphine groups to Tc(I) at all three sites trans to the carbonyl ligands.
Radiochimica Acta, Oldenbourg Wissenschaftsverlag
Print ISSN: 0033-8230
Volume: 91, 01/2003
Pages: 053