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Hisayoshi Kofujita, Youji Fujino, Michikazu Ota, Kouetsu Takahashi

Antifungal diterpenes from the bark of Cryptomeria japonica D. Don

Keywords: abietane, antifungal activity, Cryptomeria japonica, diterpene, pimarane

Bioassay-guided isolation of compounds from n-hexane extracts of the bark of Cryptomeria japonica resulted in six abietane- and two pimarane-type diterpenoids, including a new compound, 12-methoxy-6?,11-dihydroxyabieta-8,11,13-triene. The structure of the new substance was established by spectral analyses and comparison with related compounds. The antifungal activities of these diterpenes were evaluated against the phytopathogenic fungi Alternaria alternata, Pyricularia oryzae, Rhizoctonia solani and Fusarium oxysporum. The diterpenes showed moderate antifungal activity against the fungi examined.

Holzforschung, Walter de Gruyter

Print ISSN: 0018-3830
Volume: 60, 01/2006
Pages: 20 - 23

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